Mạng Lưới Tin Sinh Học Tại Việt Nam

Bioinformatics Network in Vietnam

Phần Mềm - Chương Trình

English

 

Phần mềm thông dụng

Những phần mềm thông dụng trong sinh học phân tử

Hệ điều hành Windows

Hệ điều hành Linux

ClustalX Pymol    
TreeView SpdbV    
FastPCR Rasmol    
       

 

Danh sách phần mềm sắp xếp theo chủ đề (nguồn bioinformatics.org)

3D structure visualization

PyMol PyMOL is a molecular graphics system with an embedded Python interpreter designed for real-time visualization and rapid generation of high-quality molecular graphics images and animations.

ABI

autoseq a small package of base calling software for ABI automated DNA sequencers
phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.
Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.

ABI DNA Sequencer

autoseq a small package of base calling software for ABI automated DNA sequencers

affine gap

JAligner JAligner is a Java implementation of biological sequence alignment algorithms.

alignment

Blixem Blixem, which stands for "BLast matches In an X-windows Embedded Multiple alignment", is an interactive browser of pairwise Blast matches that have been stacked up in a "master-slave" multiple alignment.
Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
DCSE DCSE (Dedicated Comparative Sequence Editor) is a multiple alignment editor
Deep View Swiss-PdbViewer Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time
DIALIGN DIALIGN is an alignment program that relies on comparison of whole segments of the sequences instead of comparison of single residue
gBioSeq Biological sequence (ADN, protein) editor for GTK/Linux
JAligner JAligner is a Java implementation of biological sequence alignment algorithms.
Jalview Jalview - a java multiple alignment editor
Mauve Mauve is a multiple genome alignment and visualization package that considers large-scale rearrangements in addition to nucleotide substitution and indels.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
MUSCLE Multiple sequence alignment. More accurate than T-Coffee, faster than CLUSTALW.
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
SAM equence Alignment and Modeling Syste a collection of flexible software tools for creating, refining, and using linear hidden Markov models for biological sequence analysis
seaview SeaView is a graphical multiple sequence alignment editor
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms
xsact EST clustering tool

alignment editor

DCSE DCSE (Dedicated Comparative Sequence Editor) is a multiple alignment editor
gBioSeq Biological sequence (ADN, protein) editor for GTK/Linux
Jalview Jalview - a java multiple alignment editor
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
seaview SeaView is a graphical multiple sequence alignment editor

alignment program

DIALIGN DIALIGN is an alignment program that relies on comparison of whole segments of the sequences instead of comparison of single residue

alignment viewer

Blixem Blixem, which stands for "BLast matches In an X-windows Embedded Multiple alignment", is an interactive browser of pairwise Blast matches that have been stacked up in a "master-slave" multiple alignment.

amplification

Amplicon Program for designing group-specific PCR primer sets

analysis

ARB Microbiologist's sequence database tool
BioJava The BioJava Project is an open-source project dedicated to providing Java tools for processing biological data.
Biopython The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology.
BioWish Biowish is a C-extension for the Tcl/Tk scripting language
Blast BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases
caRNAc RNA secondary structure inference for set of homologous sequences
Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
CNS The 'Crystallography & NMR System' for macromolecular structure anaylsis
DNA-GUI DNA Graphical User Interface
EMBOSS EMBOSS is a package of high-quality FREE Open Source software for sequence analysis.
Friend Friend, an Integrated Front-end Application for Bioinformatics
MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.
MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.
NCRNASCAN a structural RNA genefinder
PatScan PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input
PKNOTS RNA pseudoknot prediction
Pratt a pattern discovery tool
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.
readseq Reads and writes nucleic/protein sequences in various format
SEALS SEALS (A System for Easy Analysis of Lots of Sequences) is a software package expressly designed for large-scale research projects in bioinformatics.
sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format
Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.
Teiresias-based Association Discovery Discover associations in your data set (gene expression analysis, phenotype analysis, etc.)
Teiresias-based Gene expression analysis Discover patterns in microarray data using the Teiresias algorithm. Allows discovery of inversely regulated genes.
Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.
TREE-PUZZLE: TREE-PUZZLE: Maximum likelihood analysis for nucleotide, amino acid, and two-state data
tRNAscan-SE tRNA detection in genome sequences, detects ~99% of eukaryotic nuclear or prokaryotic tRNA genes, with a false positive rate of less than one per 15 gigabases, and with a search speed of about 30 kb/second.
UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments
VEGA VEGA was developed to create a bridge between most of the molecular software packages, like BioDock, Quanta/CHARMm, Insight II, MoPac, etc. In this tool have been also implemented some features that are useful to analyze, display and manage the 3D struct
WU-Blast Washington U. Blast

analytical ultracentrifugation

UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

Aneda

MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.

assembly

consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies
phrap a program for assembling shotgun DNA sequence data
Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.

automated phylogenetic analysis

PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.

base calling

autoseq a small package of base calling software for ABI automated DNA sequencers
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

Bayesian

PAML Phylogenetic Analysis by Maximum Likelihood
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

Bayesian methods

PAML Phylogenetic Analysis by Maximum Likelihood

BioCoRE

NAMD NAMD is a parallel, object-oriented molecular dynamics code designed for high-performance simulation of large biomolecular systems.

bioinformatics

Friend Friend, an Integrated Front-end Application for Bioinformatics

biological macromolecule

Garlic a free molecular visualization program

biological sequence editor

SeqPup SeqPup biological sequence editor and analysis program

biosequence

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.

blast

Blixem Blixem, which stands for "BLast matches In an X-windows Embedded Multiple alignment", is an interactive browser of pairwise Blast matches that have been stacked up in a "master-slave" multiple alignment.
DBWatcher DBWatcher is a program handling periodic BLAST searches to find similarities to your own sequences.
mpiBLAST mpiBLAST is a parallel implementation of NCBI-BLAST that uses database segmentation. It achieves a super-linear speedup in some cases.
MSPcrunch a BLAST enhancement filter
WU-Blast Washington U. Blast

blast filter

Blixem Blixem, which stands for "BLast matches In an X-windows Embedded Multiple alignment", is an interactive browser of pairwise Blast matches that have been stacked up in a "master-slave" multiple alignment.
MSPcrunch a BLAST enhancement filter

bond and atom rendering

Spock a full-featured molecular graphics program

C.elegans

Angler A Browser of C.elegans Embryo Development In Time and Space

cafasp

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

casp

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

chemical kinetics enzyme kinetics combustion catalyst reactor CSTR modeling software

Kintecus Run chemical kinetics/fitting of catalyst reactor, and enzyme reactions

chemical structures

MOPAC7 a general-purpose semi-empirical molecular orbital package for the study of chemical structures and reactions.

chromatogram

io_lib An open source C library of sequence trace files supporting ABI, ALF, SCF, CTF and ZTR file formats.
phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

code generators

Sight Allows programming free assembling of web resoureces, local executables and ssh services into arbitrary workflow.

comparative analysis

caRNAc RNA secondary structure inference for set of homologous sequences

Comparative genetics

GenomePixelizer Genome Visualization Tool: Detection of duplicating events in genomes, Displaying the Genetic Maps, Comparative genetics in general.

composition

RNA GENiE A web based program for the prediction of rna genes in genomic DNA sequences

correlation

GenomeInspector Software for the analysis of spatial correlations of elements on DNA sequences
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

crystallography

CNS The 'Crystallography & NMR System' for macromolecular structure anaylsis

data analysis

UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

data flow

Sight Allows programming free assembling of web resoureces, local executables and ssh services into arbitrary workflow.

data mining

Teiresias-based Association Discovery Discover associations in your data set (gene expression analysis, phenotype analysis, etc.)
Teiresias-based Gene expression analysis Discover patterns in microarray data using the Teiresias algorithm. Allows discovery of inversely regulated genes.

database

Acedb Acedb is a genome database system originally developed for the C.elegans genome project
ARB Microbiologist's sequence database tool
Friend Friend, an Integrated Front-end Application for Bioinformatics
HMMER Profile hidden Markov models for biological sequence analysis
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
mpiBLAST mpiBLAST is a parallel implementation of NCBI-BLAST that uses database segmentation. It achieves a super-linear speedup in some cases.

database interface

ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.

database searching

HMMER Profile hidden Markov models for biological sequence analysis

database segmentation

mpiBLAST mpiBLAST is a parallel implementation of NCBI-BLAST that uses database segmentation. It achieves a super-linear speedup in some cases.

denaturation

MeltSim Calculation of DNA melting curves and maps using the Poland-Scheraga algorithm and empirical constraints by R.D. Blake.

dictionary

Leksbot an explanatory dictionary of botanic and biological terms

distance correlations

GenomeInspector Software for the analysis of spatial correlations of elements on DNA sequences

DNA melting

MeltSim Calculation of DNA melting curves and maps using the Poland-Scheraga algorithm and empirical constraints by R.D. Blake.

DNA sequence viewer

Artemis a DNA sequence viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation.

DNA sequencing

consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies
phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

DNA structure

Garlic a free molecular visualization program

drawing

PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

Duplications

GEANFAMMER GEnome ANalysis and Protein FAMily MakER
GenomePixelizer Genome Visualization Tool: Detection of duplicating events in genomes, Displaying the Genetic Maps, Comparative genetics in general.
PhyloGrapher PhyloGrapher is a program designed to visualize and study evolutional relationship between families of homologous genes or proteins. PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes based on distance matrix file.

duplications.

PhyloGrapher PhyloGrapher is a program designed to visualize and study evolutional relationship between families of homologous genes or proteins. PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes based on distance matrix file.

electron density maps

Deep View Swiss-PdbViewer Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time

embl

consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies
phrap a program for assembling shotgun DNA sequence data
sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format
Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.

emboss

Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.

EST

SEPON SEPON designs gene-specific oligonucleotides for microarray experiments and is able to use EST input from organisms in which the genome is not annotated for genes. SEPON implements a novel algorithm for reducing cross-hybridization by utilizing thermodyna
xsact EST clustering tool

EST clustering similarity alignment

xsact EST clustering tool

eva

GRS A Graphic Tool for Genome Retrieval and Segment Analysis
LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

evolution

GenomePixelizer Genome Visualization Tool: Detection of duplicating events in genomes, Displaying the Genetic Maps, Comparative genetics in general.
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

Evolution.

GenomePixelizer Genome Visualization Tool: Detection of duplicating events in genomes, Displaying the Genetic Maps, Comparative genetics in general.

exons

Abacus ABaCUS is a no-frills program developed to investigate the significance of the putative correspondence between exons and units of protein structure.

extension

BioWish Biowish is a C-extension for the Tcl/Tk scripting language

file conversion surface mapping

VEGA VEGA was developed to create a bridge between most of the molecular software packages, like BioDock, Quanta/CHARMm, Insight II, MoPac, etc. In this tool have been also implemented some features that are useful to analyze, display and manage the 3D struct

finite element

UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

fold recognition

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

format converter

Babel a program designed to interconvert a number of file formats currently used in molecular modeling

friend

Friend Friend, an Integrated Front-end Application for Bioinformatics

GenBank Entry Visualization

GeneView II Interactive GenBank Entry Visualization

gene duplications

GEANFAMMER GEnome ANalysis and Protein FAMily MakER

gene expression

MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.
Teiresias-based Association Discovery Discover associations in your data set (gene expression analysis, phenotype analysis, etc.)

gene expression analysis

Teiresias-based Association Discovery Discover associations in your data set (gene expression analysis, phenotype analysis, etc.)

gene finding

VEIL A hidden Markov model for finding genes in vertebrate DNA?

gene regulation

Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.

gene-expression

SEPON SEPON designs gene-specific oligonucleotides for microarray experiments and is able to use EST input from organisms in which the genome is not annotated for genes. SEPON implements a novel algorithm for reducing cross-hybridization by utilizing thermodyna

gene-finding

geneid Gene prediction tool, it can also introduce homology and annotation evidences and produce a reannotation of a genomic sequence. A pthreads parallel version also available.

gene-prediction

geneid Gene prediction tool, it can also introduce homology and annotation evidences and produce a reannotation of a genomic sequence. A pthreads parallel version also available.

genetic distances

Populations Population genetic software (individuals or populations distances, phylogenetic trees)

genome annotation

Artemis a DNA sequence viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation.
Ensembl software system which produces and maintains automatic annotation on eukaryoticgenomes
On-line Genome Annotations Annotations for many eukaryotic, bacterial and archaeal genomes. Can be searched using accession numbers or sought features

genome annotations

On-line Genome Annotations Annotations for many eukaryotic, bacterial and archaeal genomes. Can be searched using accession numbers or sought features

genome development library C++ sequence manipulation GenBank DNAstar FastA

libGenome A cross platform C++ development library to manipulate DNA and protein sequences. It can read and write sequence and annotation data in several file formats.

genome rearrangement inversion locator large-scale recombination

GRIL GRIL automates the process of identifying large-scale genome inversions and rearrangements

Genome Retrieval

GRS A Graphic Tool for Genome Retrieval and Segment Analysis

Genomes

GenomePixelizer Genome Visualization Tool: Detection of duplicating events in genomes, Displaying the Genetic Maps, Comparative genetics in general.

genomic annotation

gff2ps Converting genomic annotations in GFF format to PostScript

genomic database system

Acedb Acedb is a genome database system originally developed for the C.elegans genome project

genomics

Clann Clann: Software for investigating phylogenomic information using supertrees. This implements several methods of Supertree analysis (which are used as optimality criteria) and allows exhaustive and heuristic searches of tree-space to find the best supert
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.

GFF

gff2ps Converting genomic annotations in GFF format to PostScript

global fitting

UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

gotoh's improvement


Warning: mysql_fetch_array(): supplied argument is not a valid MySQL result resource in /mnt/nfs0/www/html/software/mol_linux_cat.php3 on line 66
 

Graph theory

PhyloGrapher PhyloGrapher is a program designed to visualize and study evolutional relationship between families of homologous genes or proteins. PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes based on distance matrix file.

grep

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.

group-specific

Amplicon Program for designing group-specific PCR primer sets

Hidden Markov Models

HMMER Profile hidden Markov models for biological sequence analysis
SAM equence Alignment and Modeling Syste a collection of flexible software tools for creating, refining, and using linear hidden Markov models for biological sequence analysis

HMM

VEIL A hidden Markov model for finding genes in vertebrate DNA?

homologous genes

PhyloGrapher PhyloGrapher is a program designed to visualize and study evolutional relationship between families of homologous genes or proteins. PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes based on distance matrix file.

inference

MOLPHY A Computer Program Package for Molecular Phylogenetics including ProtML
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

java

Artemis a DNA sequence viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation.
BioJava The BioJava Project is an open-source project dedicated to providing Java tools for processing biological data.
MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.

library

Friend Friend, an Integrated Front-end Application for Bioinformatics
libGenome A cross platform C++ development library to manipulate DNA and protein sequences. It can read and write sequence and annotation data in several file formats.

maximum likelihood

fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences
MOLPHY A Computer Program Package for Molecular Phylogenetics including ProtML
PAML Phylogenetic Analysis by Maximum Likelihood
TREE-PUZZLE: TREE-PUZZLE: Maximum likelihood analysis for nucleotide, amino acid, and two-state data

Maximum likelihood analysis

TREE-PUZZLE: TREE-PUZZLE: Maximum likelihood analysis for nucleotide, amino acid, and two-state data

Maximum Likelihood Inference of Protein Phylogeny

MOLPHY A Computer Program Package for Molecular Phylogenetics including ProtML

maximum likelihood phylogenetic trees

fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences

MCMC

PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

medline

BioMail automate searching for recent scientific papers in the PubMed Medline database

melting temperature

MELTING Accurate computation of the enthalpy, entropie and melting temperature of a nucleic acid duplex

microarray

MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.
SEPON SEPON designs gene-specific oligonucleotides for microarray experiments and is able to use EST input from organisms in which the genome is not annotated for genes. SEPON implements a novel algorithm for reducing cross-hybridization by utilizing thermodyna
Teiresias-based Gene expression analysis Discover patterns in microarray data using the Teiresias algorithm. Allows discovery of inversely regulated genes.

microarray analysis

MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.
Teiresias-based Gene expression analysis Discover patterns in microarray data using the Teiresias algorithm. Allows discovery of inversely regulated genes.

microarray analysis software

MAExplorer The Microarray Explorer (MAExplorer) is a Java-based data-mining facility for microarray databases run as a stand-alone program. It includes graphics, statistics, clustering, reports, data filtering.

modeling

AMMP a modern full-featured molecular mechanics, dynamics and modeling program.
Kintecus Run chemical kinetics/fitting of catalyst reactor, and enzyme reactions
MMTK-2.2 molecular modeling tool-kit 2.2
Oslet A molecular modeling and simulation environment in Java, mainly for education.
WHAT IF WHAT IF is a versatile protein structure analysis program that can be used for mutant prediction, structure verification, molecular graphics, etc

Molecular Dynamics high performance simulator

Gromacs The World' s fastest Molecular Dynamics - and it' s gpl

molecular dynamics modeling pdb force field

MMTK-2.2 molecular modeling tool-kit 2.2

molecular dynamics simulations

GDIS a GTK based program for the display and manipulation of isolated molecules and periodic systems

molecular editor

PyMol PyMOL is a molecular graphics system with an embedded Python interpreter designed for real-time visualization and rapid generation of high-quality molecular graphics images and animations.

molecular graphics

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
Oslet A molecular modeling and simulation environment in Java, mainly for education.
Spock a full-featured molecular graphics program

molecular mechanics

AMMP a modern full-featured molecular mechanics, dynamics and modeling program.

molecular modeling

Oslet A molecular modeling and simulation environment in Java, mainly for education.
WHAT IF WHAT IF is a versatile protein structure analysis program that can be used for mutant prediction, structure verification, molecular graphics, etc

molecular modelling

Babel a program designed to interconvert a number of file formats currently used in molecular modeling

molecular rendering

Garlic a free molecular visualization program

molecular simulations

Oslet A molecular modeling and simulation environment in Java, mainly for education.

molecular structure analysis

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin

molecular visualization

Garlic a free molecular visualization program
rasmol RasMol is a free program which displays molecular structure.
VEGA VEGA was developed to create a bridge between most of the molecular software packages, like BioDock, Quanta/CHARMm, Insight II, MoPac, etc. In this tool have been also implemented some features that are useful to analyze, display and manage the 3D struct
VMD VMD is a molecular visualization program for displaying, animating, and analyzing large biomolecular systems using 3-D graphics and built-in scripting

molecular visualization program

Garlic a free molecular visualization program

molecular weight

XMolCalc a small utility that allows you to calculate a molecular weight

monte carlo

UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

motif

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.
RNABOB RNABOB -- fast RNA motif/pattern searcher

MPI

mpiBLAST mpiBLAST is a parallel implementation of NCBI-BLAST that uses database segmentation. It achieves a super-linear speedup in some cases.

multiple

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
DCSE DCSE (Dedicated Comparative Sequence Editor) is a multiple alignment editor
Friend Friend, an Integrated Front-end Application for Bioinformatics
Jalview Jalview - a java multiple alignment editor
Mauve Mauve is a multiple genome alignment and visualization package that considers large-scale rearrangements in addition to nucleotide substitution and indels.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
MUSCLE Multiple sequence alignment. More accurate than T-Coffee, faster than CLUSTALW.
seaview SeaView is a graphical multiple sequence alignment editor
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

multiple alignment editor

DCSE DCSE (Dedicated Comparative Sequence Editor) is a multiple alignment editor
Jalview Jalview - a java multiple alignment editor
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.

multiple genome alignment comparison rearrangement

Mauve Mauve is a multiple genome alignment and visualization package that considers large-scale rearrangements in addition to nucleotide substitution and indels.

multiple protein structure visualization

ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.

multiple sequence alignment

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
MUSCLE Multiple sequence alignment. More accurate than T-Coffee, faster than CLUSTALW.
seaview SeaView is a graphical multiple sequence alignment editor
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

multiple sequence alignment analys is

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin

multiple sequence alignment drawing program

ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

mysql

Ensembl software system which produces and maintains automatic annotation on eukaryoticgenomes

NAMD

NAMD NAMD is a parallel, object-oriented molecular dynamics code designed for high-performance simulation of large biomolecular systems.

neural networks

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

neural net

RNA GENiE A web based program for the prediction of rna genes in genomic DNA sequences

nmr

CNS The 'Crystallography & NMR System' for macromolecular structure anaylsis

nucleic acid

MELTING Accurate computation of the enthalpy, entropie and melting temperature of a nucleic acid duplex

oligonucleotide

Amplicon Program for designing group-specific PCR primer sets
SEPON SEPON designs gene-specific oligonucleotides for microarray experiments and is able to use EST input from organisms in which the genome is not annotated for genes. SEPON implements a novel algorithm for reducing cross-hybridization by utilizing thermodyna

online searching

MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.

online tools

On-line Genome Annotations Annotations for many eukaryotic, bacterial and archaeal genomes. Can be searched using accession numbers or sought features

parallel

mpiBLAST mpiBLAST is a parallel implementation of NCBI-BLAST that uses database segmentation. It achieves a super-linear speedup in some cases.

pattern

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
PatScan PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input
Pratt a pattern discovery tool

pattern discovery

Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery

pattern matcher

PatScan PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input

pattern matching

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.

PCR

Amplicon Program for designing group-specific PCR primer sets

PDB

Garlic a free molecular visualization program
MMTK-2.2 molecular modeling tool-kit 2.2

perl

GEANFAMMER GEnome ANalysis and Protein FAMily MakER

Phase

PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

phenotype analysis

Teiresias-based Association Discovery Discover associations in your data set (gene expression analysis, phenotype analysis, etc.)

phylogenetic

ATV a phylogenetic tree display tool
fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences
njplot NJplot is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format
PAML Phylogenetic Analysis by Maximum Likelihood
Paup Software package for inference of evolutionary trees
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.
PHYLIP PHYLIP is a free package of programs for inferring phylogenies.
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
phylowin Phylo_win is a graphical colour interface for molecular phylogenetic inference.
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.
unrooted Unrooted is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format in an unrooted way, that is, using a circular shape, with labels aligned with terminal branches.

phylogenetic tree

ATV a phylogenetic tree display tool
fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences
njplot NJplot is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format
PAML Phylogenetic Analysis by Maximum Likelihood
Paup Software package for inference of evolutionary trees
PHYLIP PHYLIP is a free package of programs for inferring phylogenies.
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
phylowin Phylo_win is a graphical colour interface for molecular phylogenetic inference.
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.
unrooted Unrooted is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format in an unrooted way, that is, using a circular shape, with labels aligned with terminal branches.

Phylogenetic tree reconstruction

PAML Phylogenetic Analysis by Maximum Likelihood

phylogenetic trees

ATV a phylogenetic tree display tool
fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences
njplot NJplot is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format
Paup Software package for inference of evolutionary trees
PHYLIP PHYLIP is a free package of programs for inferring phylogenies.
phylowin Phylo_win is a graphical colour interface for molecular phylogenetic inference.
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.
unrooted Unrooted is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format in an unrooted way, that is, using a circular shape, with labels aligned with terminal branches.

phylogenomics

Clann Clann: Software for investigating phylogenomic information using supertrees. This implements several methods of Supertree analysis (which are used as optimality criteria) and allows exhaustive and heuristic searches of tree-space to find the best supert
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.

Phylogenomics phylogeny tree supertree genomic

Clann Clann: Software for investigating phylogenomic information using supertrees. This implements several methods of Supertree analysis (which are used as optimality criteria) and allows exhaustive and heuristic searches of tree-space to find the best supert

Phylogeny

Clann Clann: Software for investigating phylogenomic information using supertrees. This implements several methods of Supertree analysis (which are used as optimality criteria) and allows exhaustive and heuristic searches of tree-space to find the best supert
Friend Friend, an Integrated Front-end Application for Bioinformatics
MOLPHY A Computer Program Package for Molecular Phylogenetics including ProtML
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.
PhyloGrapher PhyloGrapher is a program designed to visualize and study evolutional relationship between families of homologous genes or proteins. PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes based on distance matrix file.

PostScript

gff2ps Converting genomic annotations in GFF format to PostScript

POV-Ray scenes

Deep View Swiss-PdbViewer Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time

prediction

caRNAc RNA secondary structure inference for set of homologous sequences
ConsInspector A tool for the prediction of protein binding sites in nucleic acids
geneid Gene prediction tool, it can also introduce homology and annotation evidences and produce a reannotation of a genomic sequence. A pthreads parallel version also available.
LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

primer

Amplicon Program for designing group-specific PCR primer sets
primer a program for picking primers for PCR reaction

primer selection

primer a program for picking primers for PCR reaction

program

DIALIGN DIALIGN is an alignment program that relies on comparison of whole segments of the sequences instead of comparison of single residue
Garlic a free molecular visualization program
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

PROSITE

ProSA ProSA is a useful web application for finding known protein domains in nucleotide/protein sequences via PROSITE database searching

protein binding sites

ConsInspector A tool for the prediction of protein binding sites in nucleic acids

protein docking

ZDOCK Protein-protein complex structure prediction software

protein domains

DomainFinder DomainFinder 1.0 DomainFinder is an interactive program for the determination and characterization of dynamical domains in proteins
ProSA ProSA is a useful web application for finding known protein domains in nucleotide/protein sequences via PROSITE database searching

protein families

GEANFAMMER GEnome ANalysis and Protein FAMily MakER

protein interaction

ZDOCK Protein-protein complex structure prediction software

protein modelling

BRAGI BRAGI is a interactive protein modelling and display program. It was developed for the special purpose to modell unknown proteins from the structure of a known one

protein structure

Abacus ABaCUS is a no-frills program developed to investigate the significance of the putative correspondence between exons and units of protein structure.
Garlic a free molecular visualization program
LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results
MODELLER a program for homology protein structure modelling by satisfaction of spatial restraints.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.

protein structure modelling

MODELLER a program for homology protein structure modelling by satisfaction of spatial restraints.

protein structure prediction

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

protein/DNA/RNA family clustering

ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.

pubmed

BioMail automate searching for recent scientific papers in the PubMed Medline database

python

Biopython The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology.
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.

real-time visualization

PyMol PyMOL is a molecular graphics system with an embedded Python interpreter designed for real-time visualization and rapid generation of high-quality molecular graphics images and animations.

reannotation

geneid Gene prediction tool, it can also introduce homology and annotation evidences and produce a reannotation of a genomic sequence. A pthreads parallel version also available.

regex

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.

regular expression

Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.

regulatory sequence analysis

Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.

rendered animations

GDIS a GTK based program for the display and manipulation of isolated molecules and periodic systems

RNA

caRNAc RNA secondary structure inference for set of homologous sequences
caRNAsta Comparative Analysis of RNA structures by Tree Alignment
cove COVE is an implementation of stochastic context free grammar methods for RNA sequence/structure analysis.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
NCRNASCAN a structural RNA genefinder
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.
PKNOTS RNA pseudoknot prediction
RNA GENiE A web based program for the prediction of rna genes in genomic DNA sequences
RNABOB RNABOB -- fast RNA motif/pattern searcher
RnaViz a user-friendly, portable, GUI program for producing publication-quality secondary structure drawings of RNA molecules. Drawings
tRNAscan-SE tRNA detection in genome sequences, detects ~99% of eukaryotic nuclear or prokaryotic tRNA genes, with a false positive rate of less than one per 15 gigabases, and with a search speed of about 30 kb/second.
Vienna RNA Package RNA Secondary Structure Prediction and Comparison

RNA folding

Vienna RNA Package RNA Secondary Structure Prediction and Comparison

RNA gene finder

NCRNASCAN a structural RNA genefinder

RNA motif

RNABOB RNABOB -- fast RNA motif/pattern searcher

RNA pseudoknots

PKNOTS RNA pseudoknot prediction

RNA secondary structure

caRNAsta Comparative Analysis of RNA structures by Tree Alignment
cove COVE is an implementation of stochastic context free grammar methods for RNA sequence/structure analysis.

RNA secondary structures

caRNAsta Comparative Analysis of RNA structures by Tree Alignment

SCF

phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

secondary structure

caRNAsta Comparative Analysis of RNA structures by Tree Alignment
cove COVE is an implementation of stochastic context free grammar methods for RNA sequence/structure analysis.
RnaViz a user-friendly, portable, GUI program for producing publication-quality secondary structure drawings of RNA molecules. Drawings

SEPON

SEPON SEPON designs gene-specific oligonucleotides for microarray experiments and is able to use EST input from organisms in which the genome is not annotated for genes. SEPON implements a novel algorithm for reducing cross-hybridization by utilizing thermodyna

sequence

ARB Microbiologist's sequence database tool
Artemis a DNA sequence viewer and annotation tool that allows visualization of sequence features and the results of analyses within the context of the sequence, and its six-frame translation.
autoseq a small package of base calling software for ABI automated DNA sequencers
Biogrep A grep that is optimized for biosequences. Biogrep is designed to locate large sets of patterns in sequence databases in parallel.
BioJava The BioJava Project is an open-source project dedicated to providing Java tools for processing biological data.
Biopython The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology.
BioWish Biowish is a C-extension for the Tcl/Tk scripting language
Blast BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases
Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies
DBWatcher DBWatcher is a program handling periodic BLAST searches to find similarities to your own sequences.
DNA-GUI DNA Graphical User Interface
EMBOSS EMBOSS is a package of high-quality FREE Open Source software for sequence analysis.
Friend Friend, an Integrated Front-end Application for Bioinformatics
gBioSeq Biological sequence (ADN, protein) editor for GTK/Linux
Genpak a set of small utilities written in ANSI C to manipulate DNA sequences in a Unix fashion, fit for combining within shell and cgi scripts
JAligner JAligner is a Java implementation of biological sequence alignment algorithms.
libGenome A cross platform C++ development library to manipulate DNA and protein sequences. It can read and write sequence and annotation data in several file formats.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
MUSCLE Multiple sequence alignment. More accurate than T-Coffee, faster than CLUSTALW.
NCRNASCAN a structural RNA genefinder
PatScan PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
PKNOTS RNA pseudoknot prediction
Pratt a pattern discovery tool
readseq Reads and writes nucleic/protein sequences in various format
SAM equence Alignment and Modeling Syste a collection of flexible software tools for creating, refining, and using linear hidden Markov models for biological sequence analysis
SEALS SEALS (A System for Easy Analysis of Lots of Sequences) is a software package expressly designed for large-scale research projects in bioinformatics.
seaview SeaView is a graphical multiple sequence alignment editor
SeqPup SeqPup biological sequence editor and analysis program
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms
sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format
Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.
tRNAscan-SE tRNA detection in genome sequences, detects ~99% of eukaryotic nuclear or prokaryotic tRNA genes, with a false positive rate of less than one per 15 gigabases, and with a search speed of about 30 kb/second.
WU-Blast Washington U. Blast

Sequence Alignment

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
JAligner JAligner is a Java implementation of biological sequence alignment algorithms.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
Musca Multiple sequence alignment of aa or nucleotide sequences / uses pattern discovery
MUSCLE Multiple sequence alignment. More accurate than T-Coffee, faster than CLUSTALW.
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
SAM equence Alignment and Modeling Syste a collection of flexible software tools for creating, refining, and using linear hidden Markov models for biological sequence analysis
seaview SeaView is a graphical multiple sequence alignment editor
ShadyBox. ShadyBox. The FIRST GUI based WYSIWYG multiple sequence alignment drawing program for Major Unix platforms

sequence analysis

ARB Microbiologist's sequence database tool
BioJava The BioJava Project is an open-source project dedicated to providing Java tools for processing biological data.
Biopython The Biopython Project is an international association of developers of freely available Python tools for computational molecular biology.
BioWish Biowish is a C-extension for the Tcl/Tk scripting language
Blast BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases
clustalw The famous ClustalW multiple alignment program
clustalx Clustal X provides a window-based user interface to the ClustalW multiple alignment program
DNA-GUI DNA Graphical User Interface
EMBOSS EMBOSS is a package of high-quality FREE Open Source software for sequence analysis.
MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.
NCRNASCAN a structural RNA genefinder
PatScan PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input
PKNOTS RNA pseudoknot prediction
Pratt a pattern discovery tool
readseq Reads and writes nucleic/protein sequences in various format
SEALS SEALS (A System for Easy Analysis of Lots of Sequences) is a software package expressly designed for large-scale research projects in bioinformatics.
sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format
Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.
tRNAscan-SE tRNA detection in genome sequences, detects ~99% of eukaryotic nuclear or prokaryotic tRNA genes, with a false positive rate of less than one per 15 gigabases, and with a search speed of about 30 kb/second.
WU-Blast Washington U. Blast

sequence comparisons

DBWatcher DBWatcher is a program handling periodic BLAST searches to find similarities to your own sequences.

sequence conversion

readseq Reads and writes nucleic/protein sequences in various format
sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format

sequence database

ARB Microbiologist's sequence database tool

sequence editor

gBioSeq Biological sequence (ADN, protein) editor for GTK/Linux
SeqPup SeqPup biological sequence editor and analysis program

sequence finishing

consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies

sequence patterns

Pratt a pattern discovery tool

sequence similarity

Blast BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases

sequence utiities

Genpak a set of small utilities written in ANSI C to manipulate DNA sequences in a Unix fashion, fit for combining within shell and cgi scripts

sequences

Friend Friend, an Integrated Front-end Application for Bioinformatics

sequencing

autoseq a small package of base calling software for ABI automated DNA sequencers
consed A Unix-based Graphical Editor and Automated Finishing Program for Phrap Sequence Assemblies
phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

Smith-Waterman

JAligner JAligner is a Java implementation of biological sequence alignment algorithms.
MPSRCH MPSRCH (tm) is a suite of Smith-Waterman sequence analysis programs which run under Linux and Tru64 on Intel and Alpha.

Solid Angle calculation

Steric A Program to Calculate the Steric Size of Molecules about a Point in terms of their Cone Angles and Solid Angles, as well as their total Volumes and Projected Areas

staden

Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.

statistic mechanics

Oslet A molecular modeling and simulation environment in Java, mainly for education.

Steric Size calculation

Steric A Program to Calculate the Steric Size of Molecules about a Point in terms of their Cone Angles and Solid Angles, as well as their total Volumes and Projected Areas

structural alignments

Deep View Swiss-PdbViewer Swiss-PdbViewer is an application that provides a user friendly interface allowing to analyse several proteins at the same time

structural biology

DINO a realtime 3D visualization program for structural biology data.

structure

Abacus ABaCUS is a no-frills program developed to investigate the significance of the putative correspondence between exons and units of protein structure.
caRNAc RNA secondary structure inference for set of homologous sequences
caRNAsta Comparative Analysis of RNA structures by Tree Alignment
Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
CNS The 'Crystallography & NMR System' for macromolecular structure anaylsis
cove COVE is an implementation of stochastic context free grammar methods for RNA sequence/structure analysis.
Garlic a free molecular visualization program
LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results
MODELLER a program for homology protein structure modelling by satisfaction of spatial restraints.
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
MOPAC7 a general-purpose semi-empirical molecular orbital package for the study of chemical structures and reactions.
PyMol PyMOL is a molecular graphics system with an embedded Python interpreter designed for real-time visualization and rapid generation of high-quality molecular graphics images and animations.
RNA GENiE A web based program for the prediction of rna genes in genomic DNA sequences
RnaViz a user-friendly, portable, GUI program for producing publication-quality secondary structure drawings of RNA molecules. Drawings

structure analysis

Chimera Excellent molecular graphics package with support for a wide range of operations, i ncluding flexible molecular graphics, high resolution images for publication, user-driven analysis, multiple sequence alignment analysis, multiple model analysis, dockin
CNS The 'Crystallography & NMR System' for macromolecular structure anaylsis

structure prediction

caRNAc RNA secondary structure inference for set of homologous sequences
LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

stuctures

Friend Friend, an Integrated Front-end Application for Bioinformatics

substitution

PAML Phylogenetic Analysis by Maximum Likelihood
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

substitution rates

PAML Phylogenetic Analysis by Maximum Likelihood

swissprot

sp2fasta produce a file in FASTA format from one in SWISSPROTor EMBL flat file format

Tcl/Tk

BioWish Biowish is a C-extension for the Tcl/Tk scripting language

thermodynamics

caRNAc RNA secondary structure inference for set of homologous sequences
MELTING Accurate computation of the enthalpy, entropie and melting temperature of a nucleic acid duplex

threading

LIBELLULA LIBELLULA is a neural network based web server to evaluate fold recognition results

trace

io_lib An open source C library of sequence trace files supporting ABI, ALF, SCF, CTF and ZTR file formats.
phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.
Staden Package This is a free to academics (charge for commercial users) package including sequence assemble, trace viewing/editing and sequence analysis tools. It also includes a GUI to the free EMBOSS suite.
UltraScan UltraScan is a comprehensive GUI editing and data analysis package for hydrodynamic data from analytical ultracentrifugation experiments

trace chromatogram

io_lib An open source C library of sequence trace files supporting ABI, ALF, SCF, CTF and ZTR file formats.

trace files

phrap a program for assembling shotgun DNA sequence data
phred Phred reads DNA sequencer trace data, calls bases, assigns quality values to the bases, and writes the base calls and quality values to output files.

trajectory analysis

VEGA VEGA was developed to create a bridge between most of the molecular software packages, like BioDock, Quanta/CHARMm, Insight II, MoPac, etc. In this tool have been also implemented some features that are useful to analyze, display and manage the 3D struct

transcription factor binding sites

GenomeInspector Software for the analysis of spatial correlations of elements on DNA sequences

transcription factors

Toucan A Java tool for regulatory sequence analysis: detecting over-represented motifs and modules in sets of co-regulated genes.

tree

ATV a phylogenetic tree display tool
Clann Clann: Software for investigating phylogenomic information using supertrees. This implements several methods of Supertree analysis (which are used as optimality criteria) and allows exhaustive and heuristic searches of tree-space to find the best supert
fastDNAml Estimates maximum likelihood phylogenetic trees from nucleotide sequences
Friend Friend, an Integrated Front-end Application for Bioinformatics
njplot NJplot is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format
PAML Phylogenetic Analysis by Maximum Likelihood
Paup Software package for inference of evolutionary trees
PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.
PHYLIP PHYLIP is a free package of programs for inferring phylogenies.
PhyloDraw PhyloDraw is a drawing tool for creating phylogenetic trees. PhyloDraw supports various kinds of multialignment programs (Dialign2, Clustal-W, Phylip format, and pairwise distance matrix) and visualizes various kinds of tree diagrams, e.g. rectangular cl
phylowin Phylo_win is a graphical colour interface for molecular phylogenetic inference.
PyPhy PyPhy is a set of python scripts and modules for automatic, large-scale reconstructions of phylogenetic relationships of complete microbial genomes.
unrooted Unrooted is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format in an unrooted way, that is, using a circular shape, with labels aligned with terminal branches.

tree of life

PHASE PHASE performs molecular phylogenetic inference using maximum likelihood and Bayesian (MCMC) techniques. Specific RNA substitution models are implemented to account for the correlated mutations of paired bases in RNA helices.

tree viewer

ATV a phylogenetic tree display tool
njplot NJplot is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format
phylowin Phylo_win is a graphical colour interface for molecular phylogenetic inference.
unrooted Unrooted is a tree drawing program able to draw any binary tree expressed in the standard phylogenetic tree format in an unrooted way, that is, using a circular shape, with labels aligned with terminal branches.

tRNA searching

tRNAscan-SE tRNA detection in genome sequences, detects ~99% of eukaryotic nuclear or prokaryotic tRNA genes, with a false positive rate of less than one per 15 gigabases, and with a search speed of about 30 kb/second.

visualisation

Friend Friend, an Integrated Front-end Application for Bioinformatics

visualization

Garlic a free molecular visualization program
GeneView II Interactive GenBank Entry Visualization
gff2ps Converting genomic annotations in GFF format to PostScript
ModView ModView is a program to visualize and analyze multiple biomolecule structures and/or sequence alignments.
PyMol PyMOL is a molecular graphics system with an embedded Python interpreter designed for real-time visualization and rapid generation of high-quality molecular graphics images and animations.
rasmol RasMol is a free program which displays molecular structure.
VEGA VEGA was developed to create a bridge between most of the molecular software packages, like BioDock, Quanta/CHARMm, Insight II, MoPac, etc. In this tool have been also implemented some features that are useful to analyze, display and manage the 3D struct
VMD VMD is a molecular visualization program for displaying, animating, and analyzing large biomolecular systems using 3-D graphics and built-in scripting

VMD

NAMD NAMD is a parallel, object-oriented molecular dynamics code designed for high-performance simulation of large biomolecular systems.

Web robots

Sight Allows programming free assembling of web resoureces, local executables and ssh services into arbitrary workflow.

workflow

Sight Allows programming free assembling of web resoureces, local executables and ssh services into arbitrary workflow.

xchange biological data

OmniGene Standardizing Biological Data Interchange Through Web Services Technology

 

 



Cập nhật ngày 26/09/2006